The antigenic specificities defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions, and may resemble the epitope to which the first antibody reacts.

Dictionary of molecular biology. 2004.

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  • idiotype — idiotype. См. идиотип. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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  • idiotype — idiotypic /id ee euh tip ik/, adj. idiotypy /id ee euh tuy pee/, n. /id ee euh tuyp /, n. Immunol. the molecular arrangement of amino acids unique to the antigen binding site of a particular antibody. [1969; back formation from idiotypic or… …   Universalium

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